Synthesis, Characterization, Electrochemistry and Antimicrobial Activity of Zinc(II) Complexes of some Hydrazone Schiff Bases
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Published:
Apr 27, 2006
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Abstract
A series of hydrazone Schiff bases and their zinc(II) complexes have been synthesized, characterized and evaluated for antimicrobial activity. The new zinc(II) complexes have been prepared in ethanol media by a template condensation of hydrazides, with either ketone or aldehyde and zinc(II) acetate in the presence of triethylamine. The IR, ¹H and ¹³C NMR data indicate that the hydrazone ligands are coordinated to zinc metal. The cyclic voltammetry of these zinc complexes exhibited irreversible oxidation peaks. The electro-oxidation of Zn₂(Clhaptch)₂(py)₂ displayed a diffusion-controlled one electron transfer reaction process. The anti-microbial activity of the ligands and complexes were evaluated by plate diffusion method against some gram-positive bacteria, gram-negative bacteria and two fungi. There was growth inhibition exhibited by ligands and zinc(II) complexes against tested bacteria and fungi.
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M. Ali, H., P, S., Basirun W, J., S. M, Z., Abdullah, N., H.L, T., P.M. Nazri, L., & Syed Omar, S. R. (2006). Synthesis, Characterization, Electrochemistry and Antimicrobial Activity of Zinc(II) Complexes of some Hydrazone Schiff Bases. Malaysian Journal of Science, 25(1), 107–114. Retrieved from https://jupidi.um.edu.my/index.php/MJS/article/view/8277
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